The Reds won the Champions League for the sixth time in their history last season, and are hoping to claim this trophy for the fourth time.
Having opened their Premier League campaign with a 4-1 victory over Norwich last week, they are favourites with bet365 to come out on top in Turkey.
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Frank Lampard began his homecoming with a 4-0 thrashing against Manchester United at the weekend, but is available at to bounce back with a memorable victory here.
Seven of the last 12 encounters between this pair have resulted in draws, and you can get odds of on this one going into extra-time after a deadlocked 90 minutes.
Adrian is set to deputise in goal after Alisson picked up a calf injury against Norwich, while Sadio Mane could be fit to start after coming off the bench in that game.
N’Golo Kante, Willian and Christian Pulisic could all be in contention after being omitted from the starting line-up at Old Trafford, although Antonio Rudiger remains short of fitness and Callum Hudson-Odoi and Ruben Loftus-Cheek are both long-term absentees.
Although the scoreline was emphatic, Jurgen Klopp’s men were not completely convincing in the 4-1 win over Norwich - allowing their newly-promoted opponents a surprising number of chances.
In contrast, the Blues were far from as bad as their 4-0 defeat suggests against United, missing some presentable opportunities while making a number of basic errors at the back.
Both performances mean goalmouth action is unlikely to be hard to come by on Wednesday, with odds of well worth backing on both teams getting on target in a game that produces at least three goals.
Odds correct at the time of writing. Please gamble responsibly. SHARE THIS NEWS USING ANY OF THE BUTTON BELOW PLACE YOUR TEXT ADVERT BELOW ⬇⬇⬇